Scientists find Parkinson`s disease genes
Published: December 20, 2005
British and Belgium scientists report they have identified 570 genes that act abnormally during the development of Parkinson`s Disease.
The researchers from Imperial College London and the University of Liege, Belgium, say their research might help doctors predict the likelihood of the disease developing, and provide targets for new treatments.
The scientists use microarrays to analyze brains from Parkinson`s patients. Microarrays are laboratory chips able to identify which genes are active when different processes are occurring in the brain.
When they analyzed the brains of people with Parkinson`s, they found of all 25,000 human genes, regulation of 570 was highly abnormal in Parkinson`s brains compared with non-diseased brains.
The research marks the first study on Parkinson`s disease in which all human genes were studied.
Dr Linda Moran from Imperial College London and one of the authors of the paper, said: ‘This research shows there are a considerable number of genes associated with the development of Parkinson`s, potentially providing new clues for how to … help the increasing numbers of Parkinson`s patients.’
The research is published in the journal Neurogenetics.
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